Nigeria, Africa’s largest economy, provides an important case study of how outmigration developed. Political and economic crises, coupled with significant declines in the standard of living for all but the wealthiest Nigerians, means that anyone with both the means and the gumption to leave Nigeria attempted to do so (although now, we are witnessing some return migration and a strong sense of transnational identity among many Nigerians). This paper analyses the factors leading to significant waves of migration of Nigerians to the United States in the late twentieth century. In particular, I focus on the opportunities available for highly educated Nigerians in the U.S. and what their experiences were when they arrived. Although many of the first Nigerian immigrants came for education and had every intention of returning home, by the late 70s and early 80s, many skilled professionals were finding that a permanent return home was either inadvisable or impossible. Meanwhile, those who remained at home benefitted from remittances sent by their loved ones, but suffered the consequences of a ‘brain drain’ of skilled professionals and a decimated middle class.