The war was short, as was the Colombian state’s support for the roadbuilding plan. Once a new treaty ratified Colombian sovereignty over the contested area, the plan’s budget plummeted. During the following decades, most roads crumbled under the action of the rainforest. However, the sporadic interest of the Colombian state in Amazonia alone does not offer a comprehensive account of the plan’s failure over the twentieth century. The roads had replaced complex Indigenous transport systems, in which the Native population used their thorough knowledge of the region’s environment to take advantage of the same events that later would deteriorate the roads—such as seasonal flooding. This paper underscores that the dismissal of Indigenous environmental and geographic knowledge is a critical reason why infrastructure projects have failed in regions like the Amazon rainforest. Moreover, it contends that the Indigenous transport systems and the roads that replaced them denote two radically different ways of understanding and inhabiting the same territory.