This paper will explore the curricula and teaching materials Protestant missionaries devised for students in the context of the indigenization reform movement from a dual perspective. It asks, first, where the content of these materials originated, and how and by whom they were edited and distributed. Based on a case study of Protestant mission schools in the British parts of sub-Sahara Africa, the paper examines, secondly, how students’ responded to the forms of knowledge missionaries offered them as suited to serve their idiosyncratic needs. By tracing the production and local reception of missionary teaching materials, the paper demonstrates that the ways in which missionaries envisioned indigenous knowledge were not congruent with the notions African students had of the same. The processes by which Protestant mission schools defined and disseminated concepts of indigenous knowledge reveal, instead, how students appropriated, subverted and at times overtly contested the ideas of indigeneity they were taught, alongside other presumably firm categories of difference – including race, religion and age – thus offering a rich account of “traveling” knowledge and the competing epistemic systems in which mission schools were situated.