At the same time, however, the global crisis prompted a concerted Latin American challenge to Anglo-American political and ideological dominance. Here I focus on the intersecting labor of Latin American diplomats at the Pan American Union and at the League of Nations between 1928 and 1933. Within both both institutions, Latin American diplomats and technical advisors pushed for a new system of regional and international governance that would prevent the particularly dire effects of international crisis on weak economies. At the same time, they engaged in a regional and international diplomacy aimed at protecting “unorthodox” responses to the crisis such as national resource nationalization, the emission of paper money and new forms of economic protectionism. By looking at Latin American diplomacy in both the League of Nations and the Pan American union, I am able to show the variety of Latin American diplomatic strategies—from the regional to the global—as well as the ways in which Latin American diplomats played both institutions off of one another in their efforts to create an international “new deal” for Latin America.